Blood is collected as whole blood, as shown below
Blood can be stored as whole blood (with all of the plasma present) or, much more commonly, as packed red blood cells (PRBC's) in which about 70% of the plasma has been removed. This is done by light centrifugation, as shown below
The platelet rich plasma can then be expressed off, leaving packed red blood cells (PRBC's) as shown here
The plasma can be centrifuged heavily a second time to separate the platelet rich plasma, as shown below
The supernatant plasma can be expressed into a third bag and stored as fresh frozen plasma (FFP). The remaining platelet rich plasma is utilized as a platelet pack, as shown below
As can be seen in the above diagram, a single donation of whole blood has supplied three separate components (packed red blood cells, platelets, fresh frozen plasma) that can potentially benefit three different patients.
After the expiration date, rare or valuable blood units can be "rejuvenated" with a biochemical solution that restores much of the original biochemical environment of the RBC's. The "rejuvenated" units are "washed" with isotonic saline in an automated device and then can be transfused as a saline-red blood cell suspension within 2 to 4 hours, or these units can be stored glycerolized and frozen for up to 10 years
Blood can be stored as whole blood (with all of the plasma present) or, much more commonly, as packed red blood cells (PRBC's) in which about 70% of the plasma has been removed. This is done by light centrifugation, as shown below
The platelet rich plasma can then be expressed off, leaving packed red blood cells (PRBC's) as shown here
The plasma can be centrifuged heavily a second time to separate the platelet rich plasma, as shown below
The supernatant plasma can be expressed into a third bag and stored as fresh frozen plasma (FFP). The remaining platelet rich plasma is utilized as a platelet pack, as shown below
As can be seen in the above diagram, a single donation of whole blood has supplied three separate components (packed red blood cells, platelets, fresh frozen plasma) that can potentially benefit three different patients.
After the expiration date, rare or valuable blood units can be "rejuvenated" with a biochemical solution that restores much of the original biochemical environment of the RBC's. The "rejuvenated" units are "washed" with isotonic saline in an automated device and then can be transfused as a saline-red blood cell suspension within 2 to 4 hours, or these units can be stored glycerolized and frozen for up to 10 years
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