الواقع والحياد
14-09-2006, 11:59 AM
هذا الموضوع يهم اللي يشتغلون في معامل الكيمياء الحيويه .... و هو ما تأثير تكسر الدم على بعض التحاليل الكيميائيه ....... الموضوع هذا وجدته منشور في دراسة حديثه من مجله :
Clin Chem Lab Med 2006;44(3):311–316 2006 by Walter de Gruyter • Berlin • New York. DOI 10.1515/CCLM.2006.054
سأضع هنا خلاصه الدراسه و سارفق البحث كاملا لمن اراد قرائته ..
Results
As a result of the overnight freeze-thaw cycle, all the blood cell counts fell beyond the analytical sensitivity of the instrument (white blood cell counts -0.2= 03/mL, platelet count -5=103/mL and erythrocytes -0.1=106/mL). The results of the present investigation on hemolyzed specimens are presented in Tables1 and 2. Hemolysis interference, expressed as mean absolute and percentage relative bias, appeared to be approximately linearly dependent on the final concentration of blood cells lysate in the specimen. As expected, the addition of blood cell lysate generated a consistent and dose-dependent trend towards overestimation of ALT, AST, creatinine, CK, iron, LDH, lipase, magnesium, phosphorus, potassium and urea, Whereas mean values of albumin, ALP, chloride, GGT, glucose and sodium were substantially decreased when compared with the baseline specimens (no lysate).
Clin Chem Lab Med 2006;44(3):311–316 2006 by Walter de Gruyter • Berlin • New York. DOI 10.1515/CCLM.2006.054
سأضع هنا خلاصه الدراسه و سارفق البحث كاملا لمن اراد قرائته ..
Results
As a result of the overnight freeze-thaw cycle, all the blood cell counts fell beyond the analytical sensitivity of the instrument (white blood cell counts -0.2= 03/mL, platelet count -5=103/mL and erythrocytes -0.1=106/mL). The results of the present investigation on hemolyzed specimens are presented in Tables1 and 2. Hemolysis interference, expressed as mean absolute and percentage relative bias, appeared to be approximately linearly dependent on the final concentration of blood cells lysate in the specimen. As expected, the addition of blood cell lysate generated a consistent and dose-dependent trend towards overestimation of ALT, AST, creatinine, CK, iron, LDH, lipase, magnesium, phosphorus, potassium and urea, Whereas mean values of albumin, ALP, chloride, GGT, glucose and sodium were substantially decreased when compared with the baseline specimens (no lysate).