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folic acid &vitamin K

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  • folic acid &vitamin K

    مســـــــاء الانـــــــــــــوار..


    ممكن تفيدوني بمعلومات عن folic acid &vitamin K من ناحية..function,RDA,normal range,absorbtion,digestife,and defechency


  • #2
    Folate (folic acid), serum
    specimen: serum
    ref. range: 8.0-35.0 nmol/L
    6.0-8.0
    nmol/L: borderline low
    ********************************

    Folate deficiency is associated with three important disorders

    • macrocytic megaloblastic anaemia
    As with vitamin B12 deficiency, the correlation between serum folate level
    and peripheral blood findings is not close.

    • birth defects, particularly neural tube defects
    Studies have shown dramatic reduction in birth defects in women taking
    400µg folic acid daily, commencing prior to conception.

    • cardiovascular disease

    ********************************
    Causes of low serum folate

    • Inadequate diet – the commonest cause.
    Folate comes particularly from green
    vegetables and is destroyed by *****ng.
    Deficiency is associated with old
    age, poverty, alcoholism, anorexia

    • Malabsorption – coeliac disease, tropical sprue, giardiasis

    • Drugs – anticonvulsants, pyrimethamine, methotrexate and others

    High folate levels are due to vitamin supplements or a recent meal high in folate.
    Total body stores in a healthy individual approximate 10mg, enough to last about 6
    months if all dietary folate is removed. Recommencement of folate intake restores
    serum levels in a few days but replenishment and maintenance of body stores
    requires sustained
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    • #3
      Vitamin K

      Vitamin K is a fat-soluble vitamin which is essential for hepatic formation of
      functionally active prothrombin (Factor II) and coagulation Factors VII, IX and X.

      Although vitamin K is found in the diet, particularly green vegetables, the more
      important source is the normal bacterial flora of the bowel which synthesises the
      vitamin. Body stores last only 1-2 weeks if absorption stops.

      Deficiencies of vitamin K and Factors II, VII, IX and X can be due to pre-hepatic or
      hepatic causes.
      ان عشت فعش حرا أومت كالاشجار وقوفا


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