إعـــــــلان

تقليص
لا يوجد إعلان حتى الآن.

ماهي الامراض الجينيه التي تصيب الكبد

تقليص
X
 
  • تصفية - فلترة
  • الوقت
  • عرض
إلغاء تحديد الكل
مشاركات جديدة

  • ماهي الامراض الجينيه التي تصيب الكبد

    ماهي الامراض الجينيه التي تصيب الكبد؟؟؟؟
    :sm171::sm171:

  • #2
    يوجد عده امراض وراثيه شهيره تصيب الكبد و هى :

    Wilson's disease or hepatolenticular degeneration is an autosomal recessive genetic disorder in which copper accumulates in tissues; this manifests as neurological or psychiatric symptoms and liver disease. It is treated with medication that reduces copper absorption or removes the excess copper from the body, but occasionally a liver transplant is required.[1]
    The condition is due to mutations in the ATP7B gene. A single abnormal copy of the gene is present in 1 in 100 people, who do not develop any symptoms (they are carriers). If a child inherits the gene from both parents, they may develop Wilson's disease. Symptoms usually appear between the ages of 6 and 20 years, but cases in much older patients have been described. Wilson's disease occurs in 1 to 4 per 100,000 people.[1] Wilson's disease is named after Dr Samuel Alexander Kinnier Wilson (1878-1937), the British neurologist who first described the condition in 1912.[2]
    Haemochromatosis (American spelling hemochromatosis), is an hereditary disease characterized by excessive absorption of dietary iron resulting in a pathologic increase in total body iron stores. Humans, like virtually all animals, have no means to excrete excess iron.[1] Excess iron accumulates in tissues and organs disrupting their normal function. The most susceptible organs include the liver, adrenal glands, the heart and the pancreas; patients can present with cirrhosis, adrenal insufficiency, heart failure or diabetes. [2] The hereditary form of the disease is most common among those of Northern European ancestry, in particular those of British or Irish descent
    Alpha 1-antitrypsin deficiency (α1-antitrypsin deficiency, A1AD or Alpha-1) is a genetic disorder caused by defective production of alpha 1-antitrypsin (A1AT), leading to decreased A1AT activity in the blood and lungs, and deposition of excessive abnormal A1AT protein in liver cells.[1] There are several forms and degrees of deficiency. Severe A1A deficiency causes emphysema and/or COPD in adult life in nearly all people with the condition, as well as various liver diseases in a minority of children and adults, and occasionally more unusual problems.[2] It is treated by avoidance of damaging inhalants, by intravenous infusions of the A1AT protein, by transplantation of the liver or lungs, and by a variety of other measures, but it usually produces some degree of disability and reduced life expectancy.
    Gilbert's syndrome, often shortened to the acronym GS, is the most common hereditary cause of increased bilirubin, and is found in up to 5% of the population (though some Gastroenterologists maintain that it is closer to 10%). The main symptom is otherwise harmless jaundice which does not require treatment, caused by elevated levels of unconjugated bilirubin in the bloodstream (hyperbilirubinemia).
    Crigler-Najjar Syndrome or CNS is a rare disorder affecting the metabolism of bilirubin, a chemical formed from the breakdown of blood. The disorder results in an inherited form of non-hemolytic jaundice, often leading to brain damage in infants.
    This syndrome is divided into two types: type I and type II, which is sometimes called Arias syndrome. These two types, along with Gilbert's syndrome and Dubin-Johnson syndrome, make up the four known hereditary defects in bilirubin metabolism. Unlike Gilbert's syndrome, only a few hundred cases of CNS are known to exist.
    Dubin-Johnson syndrome is an autosomal recessive disorder which causes an increase of conjugated bilirubin without elevation of liver enzymes (ALT, AST). This condition is associated with a defect in the ability of hepatocytes to secrete conjugated bilirubin into the bile. It is usually diagnosed in early infancy.
    Rotor syndrome is a rare, relatively benign autosomal recessive bilirubin disorder of unknown origin.
    اشهد ان لا اله الا الله و ان سيدنا محمد رسول الله
    الهم استرنا فوق الارض و تحت الارض و يوم العرض عليك يا الله

    تعليق


    • #3
      شكرا عزيزي على الشرح الوافي...من هذا النوع ولا بلاش...

      تعليق


      • #4
        مشكوووور دكتور
        http://www.pc4up.com/im2jpg/1mw58625.jpg

        تعليق

        يعمل...
        X