Prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, and D-dimer are part of the conventional routine coagulation test.. Routine blood coagulation assays and D-dimer testing strongly influence clinical decision-making because they represent crucial steps in the diagnostic approach to thromboembolic and hemorrhagic disorders and in the monitoring of anticoagulant therapy with heparin or oral anticoagulants....thankx and u can ask me for more details or translation...
pt help in detrmine the efficincy of extrinsic and coomon pathway of coagulation...ptt help doctor 2 determine the effisincy of intrinsic and comon pathway of coagulation....fibrnogin is the factor that convert by action of thrombin into fibrin and by action of factor X111 help 2 stablize the secondry hemostatic plug ...... for d dimer have many defination...D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two crosslinked D fragments of the fibrinogen protein....ora dimer byproduct resulting from fibrinolysis; produced by cross linkage of d-domain fibrin monomers by activated factor XIII, fibrin stabilizing factor; present in low levels in normal animals, but found at particularly high levels in association with thrombotic and hemostatic disorders....orA fragment produced during the degradation of a clot. The D here stands for domain . Dimer indicates two identical units, in this case two identical domains. D-dimer result from complete breakdown of the clot.....wish am right and thankx...
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