السلام عليكم
عندي موضوع ترجمة وفي بعض الجمل التي اجد صعوبة في صياغتها
ارجو المساعدة وبسرعة ...
هو كتاب يتحدث عن systems biology in drug discovery
اريد معرفة مصطلح omics ماهو؟؟
اول مقطع هو:
وكلمة upregulated في هذه الجملة:
وكلمة coregulated.
حاليا بس هدول...
وشكرا كتير...
عندي موضوع ترجمة وفي بعض الجمل التي اجد صعوبة في صياغتها
ارجو المساعدة وبسرعة ...
هو كتاب يتحدث عن systems biology in drug discovery
اريد معرفة مصطلح omics ماهو؟؟
اول مقطع هو:
This review focuses on recent advances in the practical applications
of systems biology to drug discovery. Three principal approaches
are discussed (Fig. 1): informatic integration of ‘omics’ data sets
(a bottom-up approach); computer modeling of disease or organ
system physiology from cell and organ response level information
available in the literature (a top-down approach to target selection,
clinical indication and clinical trial design); and the use of complex
human cell systems themselves to interpret and predict the biological
activities of drugs and gene targets (a direct experimental approach
to cataloguing complex disease-relevant biological responses
).of systems biology to drug discovery. Three principal approaches
are discussed (Fig. 1): informatic integration of ‘omics’ data sets
(a bottom-up approach); computer modeling of disease or organ
system physiology from cell and organ response level information
available in the literature (a top-down approach to target selection,
clinical indication and clinical trial design); and the use of complex
human cell systems themselves to interpret and predict the biological
activities of drugs and gene targets (a direct experimental approach
to cataloguing complex disease-relevant biological responses
وكلمة upregulated في هذه الجملة:
For example, omics can be used to ask
what genes, proteins or phosphorylation states of proteins are
expressed or upregulated in a disease process, leading to the testable
hypothesis that the regulated species are important to disease induction
or progression
what genes, proteins or phosphorylation states of proteins are
expressed or upregulated in a disease process, leading to the testable
hypothesis that the regulated species are important to disease induction
or progression
وكلمة coregulated.
حاليا بس هدول...
وشكرا كتير...
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