1- Vitamin K antagonist :
a- warfarin
b- Heparin
c- Protein C
d- Antithrombin III
2- One of the intrinsic pathway
a- factor XI
b- factor XIII
c- factor I
d- factor VII
3- Para hemophilia is the deficiency of
a- factor VIII
b- factor IX
c- factor V
d- factor VII
4- Eosinophilia is seen in :
a- food sensitivity
b- Drug sensitivity
c- Atopic dermatitis
d- all of the above
5-Multiple myeloma is a neoplastic proliferation of:
a- lymphocytes
b- Granulocytes
c- Plasma cells
d-Monocytes
6- Test for intrinsic pathway:
a- bleeding time
b- Thrombin time
c- Prothrombin time
d- Partial thromboplastin time
7- Paul-Bunnel test is done to diagnose:
a- multiple myeloma
b- Hodgkin’s disease
c- Infectious mononucleosis
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d- all of the above
8- increased platelet count is :
a- thrombocytopenia
b- thrombopoietin
c- thrombocytosis
d- all of the above
9- Decreased platelet count is:
a- thrombocytopenia
b- Thrombopoietin
c- Thrombocytosis
d- all of the above
10- All these are causes of thrombocytopenia except:
a- cytotoxic drugs
b- Aplastic anemia
c- Hemorrhage
d- Radiotherapy
11- Prothrombin time is done to test:
a- Intrinsic pathway only
b- Extrinsic pathway only
c- Extrinsic and common pathways
d- Intrinsic and common pathways
12- Normal bleeding time by Duke’s method:
a- 2-7 minutes
b- 2-7 seconds
c- 2-4 minutes
d- 2-4 seconds
13- Normal partial thromboplastin time (PPT) is :
a- 3-4 minutes
b- 30-45 seconds
c- 12-15 seconds
d- 12-15 minutes
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14- Hemophilia A is the deficiency of :
a- factor V
b- factor VIII
c- factor IX
d- all of the above
15-the most common form of leukemia in children is:
a- acute lymphoblastic leukemia
b- Chronic lymphocytic leukemia
c- Acute myeloid leukemia
d- Chronic myeloid leukemia
16- Bence-Jones protein is present in cases of:
a- chronic myeloid myeloma
b-acute myeloid myeloma
c- Hodgkin’s lymphoma
d- multiple myeloma
17- Reed-Sternberg cells are found in cases of :
a- acute lymphoblastic leukemia
b- Non Hodgkin’s lymphoma
c- Hodgkin’s lymphoma
d- Multiple myeloma
18- Normal platelet count is :
a- 150,000 to 450,000/min3
b- 400,000 to 800,000/min3
c- 4,000 to 11,000 /min3
d- 50,000 to 100,000/min3
19- Antithrombin III inhibits:
a- factor Va
b- factor VIIIa
c- factor Xa
d- all of the above
20- Heparin potentiate the action of :
a- protein C
b- protein S
c- antithrombin III
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d- warfarin
21- Factor II of blood clotting is:
a- Christmas factor
b- Fibrinogen
c- Prothrombin
d- Thromboplastin
22- One of fibrinogen group is :
a- II
b-V
c- VII
d- IX
23- Fibrinogen is converted to soluble fibrin by:
a- prothrombin
b- Thromboplastin
c- Thrombin
d- all of the above
24- Thrombopoitin control the formation of:
a- red blood cells
b-White blood cells
c- platelets
d- non of the above
25- Normal prothrombin time (PT) is:
a- 30-45 seconds
b- 30-45 minutes
c- 12-15 seconds
d- 12-15 minutes
26- Parasitic disease is associated with:
a- monocytosis
b- Lymphocytosis
c- Basophilia
d- Eosinophilia
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27- Philadelphia chromosome is diagnostic for:
a- acute lymphoblastic leukemia
b- Acute myeloid leukemia
c- Chronic lymphocytic leukemia
d- chronic myeloid leukemia
28- Normal fibrinogen level:
a- 150-400 gm%
b- 150-400 mg%
c- 15-40 mg%
d- 15-40 gm%
29-infectious mononucleosis is caused by:
a- echo virus
b- coxsaki virus
c- Epstein Barr virus
d- Cytomegalo virus
30- Atypical lymphocytosis is seen in cases of:
a- Hodgkin’s lymphoma
b-Multiple myeloma
c- Infectious mononucleosis
d- Chronic lymphocytic leukemia
31-monospot test is done to diagnose:
a- Acute myeloid leukemia
b- Acute lymphoblastic leukemia
c- Infectious mononucleosis
d- Infectious lymphocytosis
32- The test which depend on blood platelets & capillary fragility is:
a- prothrombin time
b- Thrombin time
c- Bleeding time
d- Clotting time
33- Fibrin is broken to fibrin degradation products by the action of:
a- Prothrombin
b- Thrombin
c- Plasminogen
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d- Plasmin
34- Acute myeloid leukemia is characterized by:
a- low neutrophil alkaline phosphatase
b-Myeloblast with Auer rods
c- Neutrophil with Pleger-Huet anomaly
d- all of the above
35- Plasminogen is converted to plasmin by :
a- Heparin
b-Histamine
c- Urokinase
d- Serotonin
36- Increase D-dimers and fibrin degradation products are seen in cases of:
a- Hemophilia A
b- Vitamin K deficiency
c- Diffuse intravascular coagulation
d- Von Willebrand disease
37- Activated protein C degrades:
a- factor IXa
b- Factor VIIIa
c- Factor Xa
d- Factor Xia
38- Heparin is found in
a- Neutrophil
b- Basophil
c- Acidophil
d- all of the above
39- In hemophilia A the test which will be prolonged is
a- PT
b- PTT
c- Bleeding time
d- all of the above
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40- Bleeding due to overdose of heparin is managed by giving:
a- Vit K
b- Vit C
c- Vit A
d- Protamin sulphate
41- Streptokinase and staphylokinase convert:
a- Prothrombin to thrombin
b- Fibrinogen to fibrin
c- Soluble fibrin to insoluble fibrin
d- Plasminogen to plasmin
42- Test for platelet function:
a- Clot retraction
b- Platelet aggregation
c- Platelet adhesion
d- all of the above
43- Prolonged PT occurs in cases of deficiency of:
a- Factor III
b- Factor IV
c- FactorV
d- all of the above
44- normal thrombin time (TT):
a- 30-45 sec
b- 2-4 min
c- 3-9 min
d- 10-20 sec
45- cause of vitamin K deficiency:
a- Obstructive jaundice
b- Prolonged use of antibiotics
c- Inadequate intake
d- all of the above
46- Cause of Hyper- Coagulable state:
a- Aplastic anemia
b- Cytotxic drugs
c- Polcythemia
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d- Radiotherapy
47-Physiological cause of neutrophilia:
a- New born
b- Radiotherapy
c- Cytotoxic drugs
d- Prolonged use of antibiotics
48- Leucocytosis characterized by the presence of immature cells and high
neutrophil alkaline phosphatase:
a- chronic myeloid leukemia
b- Acute myeloid leukemia
c- Leukaemid reaction
d- non of the above
49- Normal coagulation time (CT):
a- 3-9 min
b- 3-9 sec
c- 30-40 sec
d- 30-40 min
50- The test which measures the clotting time of citrated plasma accelerated
by the addition of a clotting factor activator (kaolin) , phospholipids and
calcium:
a- coagulation time
b- Prothrombin time
c- Partial thromboplastin time
d- Thrombin time
51- The test which measures the clotting time of citrated plasma to which
thromboplastin and calcium has been added:
a- thrombin time
b- Prothrombin time
c- Coagulation time
d- Partial thromboplastin time
52- The test which is widely used as a control and follow up test to control
anticoagulant treatment:
a- APTT
b- PTT
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c- PT
d- TT
53- A disease characterized by progressive neoplastic proliferation of
immature white cell precursor:
a- acute leukemia
b- Chronic leukemia
c- Lymphoma
d-Multiple myeloma
54- The absolute lymphocyte count may be up to 300,000 or more between 70
and 90%of white cells in the blood film appear as small lymphocytes . THE
CASE IS:
a- Acute myeloid leukemia
b- Acute lymphoblastic leukemia
c- Chronic myeloid leukemia
d- Chronic lymphocytic leukemia
55- Variation in red cells size:
a- Poikilcytosis
b- Anisocytosis
c- Reticulocytosis
d- Leukocytosis
56- Dark red cells with no area of central pallor:
a- Stomatocyte
b- Sherocyte
c- Acathocyte
d- Schistocyte
57-Microcytic hypochromic anemia
a- hereditary spherocytosis
b- Sickle cell anemia
c- Iron deficiency anemia
d- Vit B12 deficiency anemia
58- Target cells are seen in cases of:
a- folic acid deficiency
b- Iron deficiency anemia
c- Vit B12 deficiency anemia
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d- Thalassemia
59- Red cells with elongated area of central pallor:
a- spherocyte
b- Schistocyte
c- Stomatocyte
d- Elliptocutes
60- ……………….. Symmetric, short , sharp projection from the red cells and
seen in iron deficiency anemia:
a- echinocyte
b- Acanthocyte
c- Elliptocyte
d- Ovalocyte
61- ………………is a condition in which the absorption of vit B12 is greatly
impaired due to failure or marked reduction of intrinsic factor secretion:
a- fauvism
b- fanconi’s anemia
c-sickle cell anemia
d- thalassemia
62- Hyperchromic cells are seen in:
a- iron deficiency anemia
b- Thalassemia
c- Hereditary spherocytosis
d- Sickle cell anemia
63- A prolonged low rate of bleeding results in:
a- normochromic anemia
b- Hypochromic anemia
c- Hyperchromic anemia
d- non of the above
64- Schilling test is done in diagnosis of:
a- iron deficiency anemia
b- Pernicious anemia
c- Aplastic anemia
d- folic acid deficiency
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65- Defective synthesis of either alpha or beta chains of normal hemoglobin
cause:
a- sickle cell anemia
b- Aplastic anemia
c- Pernicious anemia
d- Thalassemia
66- Neutrophils represent……………of circulating leukocyte:
a- 2-8%
b- 0-1%
c- 50-70 %
d- 2-4%
67- …………. are non nucleated, biconcave shaped cells:
a- platelet
b- Leukocyte
c- Erythrocyte
d- Macrophages
68- …………….. represent 50-70%of total leukocytes
a- lymphocytes
b- Neutrophils
c- Monocytes
d- Eosinophilis
69- ……………have a characteristic biffed nucleus and their cytoplasm is
filled with large refractile granules that stain red in blood smear
a- neutrophils
b- Eosinophilis
c- Basophiles
d- Lymphocytes
70- The cell which is responsible for antibody production is:
a- moncytes
b- T-lymphocytes
c- B-lymphocytes
d- Neutrophils
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