This is condition in which the individual may show false positive agglutination reaction with Anti-B and therefore misdiagnosed to have B antigen on RBCs. This can happen due to 2 reasons:
(1) In-Vivo: pateints with some bacterial infection or cancer of retum or colon can show this phenomenon. Such conditions can allow easy passage of bacteria to bloodstream causing modification of A antigen to B antigen by production of bacteria enzyme called deacetylase which modifies sugar on glycolipid of A Blood group RBCs.
Note: This happens only with A blood group patients
(2) In Vitro: Contamination of sample or anti-sera with bacteria such as E.coli which can habe B like antigen and able to react with antisera B giving false positive results.
Note: This can happen with any blood group
Hope this will be a new add up in everybody's information
(1) In-Vivo: pateints with some bacterial infection or cancer of retum or colon can show this phenomenon. Such conditions can allow easy passage of bacteria to bloodstream causing modification of A antigen to B antigen by production of bacteria enzyme called deacetylase which modifies sugar on glycolipid of A Blood group RBCs.
Note: This happens only with A blood group patients
(2) In Vitro: Contamination of sample or anti-sera with bacteria such as E.coli which can habe B like antigen and able to react with antisera B giving false positive results.
Note: This can happen with any blood group
Hope this will be a new add up in everybody's information
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