الانزيم CK يحفز التفاعل التالي داخل الجسم
CK
ATP + Creatine <-----------> ADP + (Creatine -phosphate) + H
High CK enzyme activity is detectable in muscle, heart and brain.
CK activity is also detectable in serum.
The CK [MW.: 80,000.00 D] consists of two subunits
.The subunits are signed as CK-M [M = muscle] and CK-B [B = brain]
.The combination of two subunits results in the formation of three types of isoenzymes:
CK-MM, CK-BB and the
hybrid form of CK-MB are characteristic for muscle, brain and heart, respectively.
Reference value
(Palestinian clinical laboratory tests guide, PCLTG, 2005)
Adult 2 ---- 19 U/L (at 37°C)
Levels in term of risk for coronary heart disease
Adults and Child
Critical value risk (CK-MB/Total CK) ≥ 4 % of CK.
High risk (AMI) (CK-MB/Total CK) ≥ 10 % of CK.
تقديري للجميع
CK
ATP + Creatine <-----------> ADP + (Creatine -phosphate) + H
High CK enzyme activity is detectable in muscle, heart and brain.
CK activity is also detectable in serum.
The CK [MW.: 80,000.00 D] consists of two subunits
.The subunits are signed as CK-M [M = muscle] and CK-B [B = brain]
.The combination of two subunits results in the formation of three types of isoenzymes:
CK-MM, CK-BB and the
hybrid form of CK-MB are characteristic for muscle, brain and heart, respectively.
Reference value
(Palestinian clinical laboratory tests guide, PCLTG, 2005)
Adult 2 ---- 19 U/L (at 37°C)
Levels in term of risk for coronary heart disease
Adults and Child
Critical value risk (CK-MB/Total CK) ≥ 4 % of CK.
High risk (AMI) (CK-MB/Total CK) ≥ 10 % of CK.
تقديري للجميع
تعليق