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small Quiz in ANA

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  • #1

    small Quiz in ANA



    1- ANA may result in false weak positive in :
    a- acute infections.
    b- old patients.
    c-severe burns.
    d- A&B are correct..
    e- all of the above.



    2- Confirmatory tests for ANA include :
    a- dsDNA.
    b- SM.
    c- SS-A.
    d- A&C are correct.
    e- all are correct.



    3- The volume of diluent needed to make 1/ 400 dil. of 10ul sample is :
    a- 4000 ml.
    b- 3900 ml.
    c- 3990 ml.
    d- non of the above.



    4-In anti-dsDNA test, the wells are coated with :
    a- HEP-2 cells.
    b- dsDNA .
    c- anti-dsDNA.
    d-Non of the above.



    5- ANA = 1/1280 , homo., anti-dsDNA = POSITIVE,
    Anti-SM = NEG., Anti-SS-A= POS.
    From the above results ,what is the suspected case?


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  • #2
    Anti-nuclear antibodies (ANAs, also known as anti-nuclear factor or ANF) are antibodies directed against contents of the cell nucleus.

    They are present in higher than normal numbers in autoimmune disease. The ANA test measures the pattern and amount of autoantibody which can attack the body's tissues as if they were foreign material. Autoantibodies are present in low titers in the general population, but in about 5% of the population, their concentration is increased, and about half of this 5% have an autoimmune disease.

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