Also known as:Somatomedin C Formal name:Insulin-like Growth Factor - 1 Related tests:Growth Hormone (GH), Glucose, Glucose Tolerance Test
Introduction:
IGF-1 isn't a top-secret chemical, nor is it a dangerous steroid. IGF1 is actually a natural molecular structure similar to insulin. IGF-1 is the abbreviation for Insulin-Like Growth Factor 1.Know in scientific circles as a polypeptide protein hormone, IGF-1 or Insulin-like Growth Factor 1 plays a vital role in childhood growth and stimulates anabolic effects (muscle building) in adults.
Insulin-like growth factor binding protein 3 (IGFBP-3) is the main carrier of somatomedin C (also called insulin-like growth factor-1, or IGF-1) in the body. Blood levels of both these proteins are controlled by human growth hormone (hGH), a hormone that's produced by the pituitary gland, a pea-sized gland in the brain that regulates growth and the function of other glands.
But IGFBP-3 is more than just a transporter. It also helps extend the life of somatomedin C in the blood and helps control its effects on body tissues.
Levels of IGFBP-3 are highest during childhood and puberty, then they decrease during adulthood. Levels also may be affected by sexual maturation and nutritional status.
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