Causes
1. blood loss, as in gastro intestinal anduterine haemorhage
2.Increase demands as in pregnancy , growth,and child bearing
3.Malabsorption as in gastrectomy
4. poor diet
Clinical features:1
,but with aneamia the patient may also show Glossitis,spoon- nails,dysphagia due to pharygeal
in early stage --no clincal abnormality
DIGNOSIS
1. Clinical history
2.Labratory dignosis
a. Red blood cell indices-- Mcv--- reduced less than 80 fl, Mch reduced less than 27 pg,
b. R.B.Ccount normal or low
3.Blood film : show a.
hypochromic microcytic red blood cel
b. target cell
c. pencils cell
d. in severe case with folat and B12difeiciency show dimorphic film
e. Reticulocyte count is low in relation with degreee of aneamia
4. Plate lete count------ raised
5.serum Iron----------- reduced
6. serum ferritn --------------------reduced
7.TIBC------------------------------------raised
8. Bone marrow iron store---------- absent
9.Erythroblast iron -------------------absent
10. Heamoglobin electrophoresis---------- normal
l ,
1. blood loss, as in gastro intestinal anduterine haemorhage
2.Increase demands as in pregnancy , growth,and child bearing
3.Malabsorption as in gastrectomy
4. poor diet
Clinical features:1
,but with aneamia the patient may also show Glossitis,spoon- nails,dysphagia due to pharygeal
in early stage --no clincal abnormality
DIGNOSIS
1. Clinical history
2.Labratory dignosis
a. Red blood cell indices-- Mcv--- reduced less than 80 fl, Mch reduced less than 27 pg,
b. R.B.Ccount normal or low
3.Blood film : show a.
hypochromic microcytic red blood cel
b. target cell
c. pencils cell
d. in severe case with folat and B12difeiciency show dimorphic film
e. Reticulocyte count is low in relation with degreee of aneamia
4. Plate lete count------ raised
5.serum Iron----------- reduced
6. serum ferritn --------------------reduced
7.TIBC------------------------------------raised
8. Bone marrow iron store---------- absent
9.Erythroblast iron -------------------absent
10. Heamoglobin electrophoresis---------- normal
l ,
تعليق