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PART CLINICAL CASES CASE 1 severe sore throat. Findings on physical A 22-year-old woman has a examination include an inflamed throat, swollen cervical lymph nodes, and an enlarged spleen. Her heterophile agglutinin test (Monospot test) is positive. Diagnosis: Infectious mononucleosis caused by Epstein-Barr virus. Other viruses and bacteria, especially Streptococcus pyogenes, can cause pharyngitis and cervical lymphadenopathy, but an enlarged spleen and a positive Monospot test make infectious mononucleosis the most likely diagnosis. ASE 2
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