Mediterranean or cooleys aneamia
sever aneamia after 3 - 6 months after birth when switich of gama to beta chain
Enlrgement liver and spleen due to excessive red cell destruction
Expansion of bone due to intense of marrow hypre plasia lead to tendency of fracture
Iron over load due to transfusion of blood (500 ml of blood contain 250 mg of Iro)))(
[SIZE="6"] LAB . dignosis
Severe hypochromic microcytic aneamia
Raised of Reticulocte prcentage wuth normoblast
Target cell appear
Basophilic stippling
Hb - Electrophoresis show absent of Hb A and almost H B ciculating is Hb F
sever aneamia after 3 - 6 months after birth when switich of gama to beta chain
Enlrgement liver and spleen due to excessive red cell destruction
Expansion of bone due to intense of marrow hypre plasia lead to tendency of fracture
Iron over load due to transfusion of blood (500 ml of blood contain 250 mg of Iro)))(
[SIZE="6"] LAB . dignosis
Severe hypochromic microcytic aneamia
Raised of Reticulocte prcentage wuth normoblast
Target cell appear
Basophilic stippling
Hb - Electrophoresis show absent of Hb A and almost H B ciculating is Hb F
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