Table 1 Hematology and Coagulation



Analyte Specimena SI Units Conventional Units
Activated clotting time WB 70–180 s 70–180 seconds
Activated protein C resistance (Factor V Leiden) P Not applicable Ratio > 2.1
Alpha2 antiplasmin
P 0.87–1.55 87–155%
Antiphospholipid antibody panel
PTT-LA (Lupus anticoagulant screen) P Negative Negative
Platelet neutralization procedure P Negative Negative
Dilute viper venom screen P Negative Negative
Anticardiolipin antibody S

IgG 0–15 arbitrary units 0–15 GPL
IgM 0–15 arbitrary units 0–15 MPL
Antithrombin III P
Antigenic 220–390 mg/L 22–39 mg/dL
Functional 0.7–1.30 U/L
70–130%

Anti-Xa assay (heparin assay) P
Unfractionated heparin 0.3–0.7 kIU/L 0.3–0.7 IU/mL
Low-molecular-weight heparin 0.5–1.0 kIU/L 0.5–1.0 IU/mL
Danaparoid (Orgaran) 0.5–0.8 kIU/L
0.5–0.8 IU/mL

Autohemolysis test WB 0.004–0.045 0.4%–4.50%
Autohemolysis test with glucose WB 0.003–0.007 0.3%–0.7%
Bleeding time (adult) <7.1 min <7.1 min
Bone marrow: see Table 8

Clot retraction WB 0.50–1.00/2 h 50–100%/2 h
Cryofibrinogen P Negative Negative
D-Dimer P 0.22–0.74 g/mL 0.22–0.74 g/mL
Differential blood count WB
Neutrophils 0.40–0.70 40–70%
Bands 0.0–0.05 0–5%
Lymphocytes 0.20–0.50 20–50%
Monocytes 0.04–0.08 4–8%
Eosinophils 0.0–0.6 0–6%
Basophils 0.0–0.02
0–2%

Eosinophil count WB 150–300/L 150–300/mm3

Erythrocyte count WB
Adult males 4.30–5.60 x 1012/L
4.30–5.60 x 106/mm3

Adult females 4.00–5.20 x 1012/L
4.00–5.20 x 106/mm3

Erythrocyte life span WB
Normal survival 120 days 120 days
Chromium labeled, half life (t1/2)
25–35 days
25–35 days

Erythrocyte sedimentation rate WB
Females 0–20 mm/h 0–20 mm/h
Males 0–15 mm/h
0–15 mm/h

Euglobulin lysis time P 7200–14400 s 120–240 min
Factor II, prothrombin P 0.50–1.50 50–150%
Factor V P 0.50–1.50 50–150%
Factor VII P 0.50–1.50 50–150%
Factor VIII P 0.50–1.50 50–150%
Factor IX P 0.50–1.50 50–150%
Factor X P 0.50–1.50 50–150%
Factor XI P 0.50–1.50 50–150%
Factor XII P 0.50–1.50 50–150%
Factor XIII screen P Not applicable Present
Factor inhibitor assay P < 0.5 Bethesda Units < 0.5 Bethesda Units
Fibrin(ogen) degradation products P 0–1 mg/L 0–1 g/mL
Fibrinogen P 2.33–4.96 g/L 233–496 mg/dL
Glucose-6-phosphate dehydrogenase (erythrocyte) WB < 2400 s <40 min
Ham's test (acid serum) WB Negative Negative
Hematocrit WB
Adult males 0.388–0.464 38.8–46.4
Adult females 0.354–0.444
35.4–44.4

Hemoglobin
Plasma P 6–50 mg/L 0.6–5.0 mg/dL
Whole blood WB

Adult males 133–162 g/L 13.3–16.2 g/dL
Adult females 120–158 g/L
12.0–15.8 g/dL

Hemoglobin electrophoresis WB
Hemoglobin A 0.95–0.98 95–98%
Hemoglobin A2
0.015–0.031 1.5–3.1%
Hemoglobin F 0–0.02 0–2.0%
Hemoglobins other than A, A2, or F
Absent
Absent

Heparin-induced thrombocytopenia antibody P Negative Negative
Joint fluid crystal JF Not applicable No crystals seen
Joint fluid mucin JF Not applicable Only type I mucin present
Leukocytes
Alkaline phosphatase (LAP) WB 0.2–1.6 kat/L 13–100 /L
Count (WBC) WB
3.54–9.06 x 109/L
3.54–9.06 x 103/mm3

Mean corpuscular hemoglobin (MCH) WB 26.7–31.9 pg/cell 26.7–31.9 pg/cell
Mean corpuscular hemoglobin concentration (MCHC) WB 323–359 g/L 32.3–35.9 g/dL
Mean corpuscular hemoglobin of reticulocytes (CH) WB 24–36 pg 24–36 pg
Mean corpuscular volume (MCV) WB 79–93.3 fL 79–93.3 m3

Mean platelet volume (MPV) WB 9.00–12.95 fL 9.00–12.95 m3

Osmotic fragility of erythrocytes WB
Direct 0.0035–0.0045 0.35–0.45%
Index 0.0030–0.0065
0.30–0.65%

Partial thromboplastin time, activated P 26.3–39.4 s 26.3–39.4 s
Plasminogen P
Antigen 84–140 mg/L 8.4–14.0 mg/dL
Functional 0.70–1.30
70–130%

Plasminogen activator inhibitor 1 P 4–43 g/L 4–43 ng/mL
Platelet aggregation PRP Not applicable > 65% aggregation in response to adenosine diphosphate, epinephrine, collagen, ristocetin, and arachidonic acid
Platelet count WB 165–415 x 109/L
165–415 x 103/mm3

Platelet, mean volume WB 6.4–11 fL 6.4–11.0 m3

Prekallikrein assay P 0.50–1.5 50–150%
Prekallikrein screen P No deficiency detected
Protein C P
Total antigen 0.70–1.40 70–140%
Functional 0.70–1.30
70–130%

Protein S P
Total antigen 0.70–1.40 70–140%
Functional 0.65–1.40 65–140%
Free antigen 0.70–1.40
70–140%

Prothrombin gene mutation G20210A WB Not applicable Not present
Prothrombin time P 12.7–15.4 s 12.7–15.4 s
Protoporphyrin, free erythrocyte WB 0.28–0.64 mol/L of red blood cells 16–36 g/dL of red blood cells
Red cell distribution width WB < 0.145 < 14.5%
Reptilase time P 16–23.6 s 16–23.6 s
Reticulocyte count WB
Adult males 0.008–0.023 red cells 0.8–2.3% red cells
Adult females 0.008–0.020 red cells
0.8–2.0% red cells

Reticulocyte hemoglobin content WB >26 pg/cell >26 pg/cell
Ristocetin cofactor (functional von Willebrand factor) P
Blood group O 0.75 mean of normal 75% mean of normal
Blood group A 1.05 mean of normal 105% mean of normal
Blood group B 1.15 mean of normal 115% mean of normal
Blood group AB 1.25 mean of normal
125% mean of normal

Sickle cell test WB Negative Negative
Sucrose hemolysis WB <0.1 <10% hemolysis
Thrombin time P 15.3–18.5 s 15.3–18.5 s
Total eosinophils WB 150–300 x 106/L
150–300/mm3

Transferrin receptor S, P 9.6–29.6 nmol/L 9.6–29.6 nmol/L
Viscosity
Plasma P 1.7–2.1 1.7–2.1
Serum S
1.4–1.8
1.4–1.8

Von Willebrand factor (vWF) antigen (factor VIII:R antigen) P
Blood group O 0.75 mean of normal 75% mean of normal
Blood group A 1.05 mean of normal 105% mean of normal
Blood group B 1.15 mean of normal 115% mean of normal
Blood group AB 1.25 mean of normal
125% mean of normal

Von Willebrand factor multimers P Normal distribution Normal distribution
White blood cells: see "leukocytes

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