DEFINITION
a soluble plama protein that is synthesised by the liver
fibrinogen helps stop bleeding by helping blood clots to form
major function is the prescour to fibrin
prothrombine convert soluble fibrinogen into insoluble strands of fibrin
fibinogen test orderd in the following
1-excessive bleeding
2-when prothrombin tim(PT) and partial thrombin tim(PTT )are abnormale
3-in patients with disseminated intravascular coagulation(DIC
4-in patient with cardio vascular disease
normal range# 200-400mg\dl
low level of fibrinogen indicate impair the body ability to form astable blood clot
reduced in liver disease, sever malnutrition,and in inheritted disease such as afibrinogenemia
fibrinogen reduced in people with following rapid long-volume blood transfusion
high level of fibrinogen seen in
1-acute infection
2-cardiovascular disease
3-stroke
4-inflamatory disorder such as rheumatoid arthritis
5-trauma
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