as an orginal blood group ,no it is not possible according to my knwoledge

but I think this case can be seen in the baby who has a history of blood transfusion-by other than his original group- more than his blood volum....

by the way, in this case this interpretation may not be logical ,because if
his orginal blood group is O or A, he will not be transfused by B blood
if he is in need!!!!! ...

if no history of blood transfusion by B blood group given to this baby before 3 months-no antibodies prodused yet-in my opinion this baby is not belong to this family...

Here you go , another case for those who are interested

Group B child borned in an indian family with Group O father & group A mother? Explain if it is possible to have such group in the Family?

Thank you very much for your contribution, You are quite right as far as posibilities of ABO discrepancies are concerned but if you try to concentrate on the case there are 3 keys which are:
1. Forward grouping A Rh(D) positive: assume it is correct as patient history says he is A Rh(D) positive
2. Incompatible cross match with all units screened
3. Reverse grouping shows agglutination with anti-A which not supose to be the casesame

Remember that 80% of the A group population worldwide are A1 & 20% are A2 (can produce anti-A1). Cross match with same blood group showed incomaptible because all of these units were A1 and patient serum contained anti-A1 as he is A2. Anti-A1 is cold agglutinin thats why it reacted in Immediate spin cross match. However, this is not problamatic inside body and can not cause any trabnsfusion reaction. Since patient was required urgent unit group O was correct dicision. However, providing such incompatible unit wouldnt have effected as well.

Remeber also, In reverse grouping A1 cells are used and since patient serum contains anti-A1 it reacted with A1 cells giving agglutination which was the cause of ABO discrepancy in this case.

Hope this helps

blood group is A RH +ve depend of forword
in reverse: false +ve reaction may be due to unexpected antibodies other than anti A or anti B
- in situation such as a group A individual reacting with both the A1 and B reagent cells.
- clod agglutinins are another cause of unexpected +ve in revers type
- miscellaneous problems
- patient has circulation RBCs more than one ABO group due to RBCs transfusion or bone marrow transplant
- caused by Polyagglutinantion due to exposure of hidden erythrocyte Ag
- bacterial contamination

to resolve:
incubate at 37 c for short period then washed with saline 3 times then retype
if not resolving patient red cells can be treated with 0.01 m dithiothreitol to dipers IgM - relate agglutination

in emergency give patient O compatible Rh if can if not give him O
Rh-ve

offcourse correct no doubt

أولا أشكرك على تواصلك المثمر ..

الجواب/

أعتقد انه الاب المفروض ما يتبرع لهم ,,أما السبب فهو لأنه الانتيجين اللي عند الطفل واللي تفاعل مع الاجسام المضادة اللي عند الام ما هي الا مورثة من عند الاب...

يعني الأب لو تبرع للأم ..الانتيجين اللي عند الاب ممكن يتفاعل مع الجسم المضاد اللي عند الام..."نفس التفاعل اللي صار للطفل"

والاب لو تبرع للطفل أيضا ممكن يصير تفاعل بسبب احتواء جسم الطفل على نسبة اجسام مضادة من الام...

أما العينة اللي نستخدمها عشان ال crossmatching فهي طبعا عينة الام ,,لأن الطفل مازال لم تتكون له مناعة وكل الاجسام المضادة اللي ممكن تكون عنده هي مكتسبة من الام...

إن شاء الله يكون صح:sm188:

As you wish

New born baby diagnosed to have HDFN due to antibodies against his other blood group system (non ABO, Rh). Both mother (due to delivery complications) and baby required blood transfusion. Father is willing to donate his blood? will you accept father as donor? why? what samples will you use for crossmatching?
(note: All father, mother & baby are A Rh(D) positive )

كل الشكر لتواصلك أخوي وننتظر المزيد ....

الإجابة صحيحة مائة بالمائة ماشاء الله معلوماتك جيدة

السلام عليكم/

طيب لأنه هندي على طول أشك في البومباي بلود جروب..يعني يمكن عنده ال anti -H ولأنه المتبرعين عندهم H انتيجين صار التفاعل...

عشان مايصير تفاعل للبومباي لازم ألاقي له بومباي مثله ...

للأمانة خبرتي العملية في بنك الدم ضعيفة بس هذا اللي اتذكره من أيام الدراسة ومنكم نستفيد.....

Congrats you got it. Very happy to see people want to learn and try level best to solve cases. This is what we need as Biomedical scientists, not releasing reports but taking part of interpretation as well.

Q2: New indian resident in Oman required transfusion. His forward grouping was O Rh(D) Positive, 20 O Rh(D) Positive donors showed incompatible with immediate spin crossmach. Autoagglutinin presence was excluded as a cause of such phenomenon. What could be the reason of incompatibility? Can you give him transfusion? why?

أشكرك أخت ambitious553 على المشاركة بس الفصيلة أ مو أو حاولي تفسري النتيجة على أن المريض فصيلته أ واستبعدي أي أخطاء تقنية

السلام عليكم/

يعني المريض طلعت فصيلته A وطلع عنده anti-A & anti-B ؟؟..

أولا المريض لإنقاذه أعتقد أحسن حل انه نعطيه O سالب ..

أما تفسير النتيجة أتذكر أستاذي الفاضل انني قرأت لك أحد الردود تقول فيها انه الماده نفسها ال antisera للفصيله A يوجد فيها أجسام مضادة تخلي انتيجينات على خلايا الدم الحمراء تتفاعل معاها وتعطينا بوسيتيف بالغلط... ممكن يكون هذا السبب؟؟

يعني انه الفصيلة اصلا هي "أو " وبالغلط طلعت A وحلها يكون بعمل ال wash لخلايا الدم الحمراء مثل ما تفضلت...

إذا الاجابة خطأ أبحث عن الاجابة وإن شاء الله ألاقيها ...:sm188:

كل الشكر لك ولمعلوماتك الجميلة جدا...وجزاك الله خير..